Journal Article

CNVDetector: locating copy number variations using array CGH data

Peng-An Chen, Hsiao-Fei Liu and Kun-Mao Chao

in Bioinformatics

Volume 24, issue 23, pages 2773-2775
Published in print December 2008 | ISSN: 1367-4803
Published online November 2008 | e-ISSN: 1460-2059 | DOI: http://dx.doi.org/10.1093/bioinformatics/btn517
CNVDetector: locating copy number variations using array CGH data

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Summary: CNVDetector is a program for locating copy number variations (CNVs) in a single genome. CNVDetector has several merits: (i) it can deal with the array comparative genomic hybridization data even if the noise is not normally distributed; (ii) it has a linear time kernel; (iii) its parameters can be easily selected; (iv) it evaluates the statistical significance for each CNV calling.

Availability: CNVDetector (for Windows platform) can be downloaded from http:www.csie.ntu.edu.tw/~kmchao/tools/CNVDetector/. The manual of CNVDetector is also available.

Contact: kmchao@csie.ntu.edu.tw

Supplementary information: Supplementary data are available at Bioinformatics online.

Journal Article.  1616 words.  Illustrated.

Subjects: Bioinformatics and Computational Biology

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