Journal Article

Genetic association analysis with FAMHAP: a major program update

Christine Herold and Tim Becker

in Bioinformatics

Volume 25, issue 1, pages 134-136
Published in print January 2009 | ISSN: 1367-4803
Published online November 2008 | e-ISSN: 1460-2059 | DOI: http://dx.doi.org/10.1093/bioinformatics/btn581
Genetic association analysis with FAMHAP: a major program update

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Summary: FAMHAP is an established software for haplotype association analysis of nuclear families. We have released a major update that comprises various new features for case-control data. Furthermore, weprovide an additional program runFamhap that allows users to start the same method repeatedly for varying sets of genetic markers. In addition, a platform-independent graphical user interface (GUI) was developed to simplify the usage of both FAMHAP and runFamhap. The runFamhap program greatly facilitates the application of FAMHAP to genome-wide association studies (GWAS) and supports flexible genome-wide haplotype analysis. As an example, we describe application to HapMap data.

Availability: The software is available at http://famhap.meb.uni-bonn.de

Contact: herold@imbie.meb.uni-bonn.de; becker@imbie.meb.uni-bonn.de

Supplementary information: Supplementary data are available at Bioinformatics online.

Journal Article.  2444 words. 

Subjects: Bioinformatics and Computational Biology

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