Journal Article

QMSim: a large-scale genome simulator for livestock

Mehdi Sargolzaei and Flavio S Schenkel

in Bioinformatics

Volume 25, issue 5, pages 680-681
Published in print March 2009 | ISSN: 1367-4803
Published online January 2009 | e-ISSN: 1460-2059 | DOI: http://dx.doi.org/10.1093/bioinformatics/btp045
QMSim: a large-scale genome simulator for livestock

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Summary: QMSim was designed to simulate large-scale genotyping data in multiple and complex livestock pedigrees. The simulation is basically carried out in two steps. In the first step, a historical population is simulated to establish mutation-drift equilibrium, and in the second step, recent population structures are generated, which can be very complex. A wide variety of genome architectures, ranging from infinitesimal model to single-locus model, can be simulated. The program is efficient in terms of computing time and memory requirements.

Availability: Executable versions of QMSim for Windows and Linux are freely available at http://www.aps.uoguelph.ca/~msargol/qmsim/.

Contact: msargol@uoguelph.ca

Journal Article.  1618 words. 

Subjects: Bioinformatics and Computational Biology

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