Journal Article

Seevolution: visualizing chromosome evolution

Andrés Esteban-Marcos, Aaron E. Darling and Mark A. Ragan

in Bioinformatics

Volume 25, issue 7, pages 960-961
Published in print April 2009 | ISSN: 1367-4803
Published online February 2009 | e-ISSN: 1460-2059 | DOI:

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Summary: Genome evolution underpins all of biology, yet its principles can be difficult to communicate to the non-specialist. To facilitate broader understanding of genome evolution, we have designed an interactive 3D environment that enables visualization of diverse genome evolution processes. The system can intuitively and interactively animate mutation histories involving genome rearrangement, point mutation, recombination, insertion and deletion. Multiple organisms related by a phylogeny can be visualized simultaneously. As methods to infer evolutionary histories of genomes become increasingly complex, visualization of the evolutionary process will not only be useful for communication, but will also serve as an exploratory tool for discovering new patterns of genome evolution.

Availability: The software is licensed under the GNU GPL and available for download from


Journal Article.  1070 words.  Illustrated.

Subjects: Bioinformatics and Computational Biology

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