Journal Article

Identification of ribosomal RNA genes in metagenomic fragments

Ying Huang, Paul Gilna and Weizhong Li

in Bioinformatics

Volume 25, issue 10, pages 1338-1340
Published in print May 2009 | ISSN: 1367-4803
Published online April 2009 | e-ISSN: 1460-2059 | DOI: http://dx.doi.org/10.1093/bioinformatics/btp161

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Motivation: Identification of genes coding for ribosomal RNA (rRNA) is considered an important goal in the analysis of data from metagenomics projects. Here, we report the development of a software program designed for the identification of rRNA genes from metagenomic fragments based on hidden Markov models (HMMs). This program provides rRNA gene predictions with high sensitivity and specificity on artificially fragmented genomic DNAs.

Availability: Supplementary files, scripts and sample data are available at http://tools.camera.calit2.net/camera/meta_rna.

Contact: liwz@sdsc.edu

Supplementary information: Supplementary Data are available at Bioinformatics online.

Journal Article.  1487 words. 

Subjects: Bioinformatics and Computational Biology

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