Journal Article

<i>Hooke</i>: an open software platform for force spectroscopy

Massimo Sandal, Fabrizio Benedetti, Marco Brucale, Alberto Gomez-Casado and Bruno Samorì

in Bioinformatics

Volume 25, issue 11, pages 1428-1430
Published in print June 2009 | ISSN: 1367-4803
Published online March 2009 | e-ISSN: 1460-2059 | DOI:
Hooke: an open software platform for force spectroscopy

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Summary: Hooke is an open source, extensible software intended for analysis of atomic force microscope (AFM)-based single molecule force spectroscopy (SMFS) data. We propose it as a platform on which published and new algorithms for SMFS analysis can be integrated in a standard, open fashion, as a general solution to the current lack of a standard software for SMFS data analysis. Specific features and support for file formats are coded as independent plugins. Any user can code new plugins, extending the software capabilities. Basic automated dataset filtering and semi-automatic analysis facilities are included.

Availability: Software and documentation are available at Hooke is a free software under the GNU Lesser General Public License.


Journal Article.  1888 words.  Illustrated.

Subjects: Bioinformatics and Computational Biology

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