Journal Article

BIPA: a database for protein–nucleic acid interaction in 3D structures

Semin Lee and Tom L Blundell

in Bioinformatics

Volume 25, issue 12, pages 1559-1560
Published in print June 2009 | ISSN: 1367-4803
Published online April 2009 | e-ISSN: 1460-2059 | DOI:
BIPA: a database for protein–nucleic acid interaction in 3D structures

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Summary:BIPA is a database for protein–nucleic acid interactions in 3D structures. The database provides various physicochemical features of protein–nucleic acid interface such as size, shape, residue propensity, secondary structure composition and intermolecular interactions. The database also contains multiple structural alignments of nucleic acid-binding protein families with annotations of local environments in order to allow definition of features that influence acceptability of mutations at a particular position in a protein family. A web interface has been designed to present the results of these analyses and facilitate navigation of protein–nucleic acid interfaces.


Supplementary information:Supplementary data are available at Bioinformatics online.

Journal Article.  1080 words.  Illustrated.

Subjects: Bioinformatics and Computational Biology

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