Journal Article

Genoscape: a Cytoscape plug-in to automate the retrieval and integration of gene expression data and molecular networks

Mathieu Clément-Ziza, Christophe Malabat, Christian Weber, Ivan Moszer, Tero Aittokallio, Catherine Letondal and Sandrine Rousseau

in Bioinformatics

Volume 25, issue 19, pages 2617-2618
Published in print October 2009 | ISSN: 1367-4803
Published online August 2009 | e-ISSN: 1460-2059 | DOI: http://dx.doi.org/10.1093/bioinformatics/btp464

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Summary: Genoscape is an open-source Cytoscape plug-in that visually integrates gene expression data sets from GenoScript, a transcriptomic database, and KEGG pathways into Cytoscape networks. The generated visualisation highlights gene expression changes and their statistical significance. The plug-in also allows one to browse GenoScript or import transcriptomic data from other sources through tab-separated text files. Genoscape has been successfully used by researchers to investigate the results of gene expression profiling experiments.

Availability: Genoscape is an open-source software freely available from the Genoscape webpage (http://www.pasteur.fr/recherche/unites/Gim/genoscape/). Installation instructions and tutorial can also be found at this URL.

Contact: Mathieu.clement-ziza@biotec.tu-dresden.de; sandrine.rousseau@pasteur.fr

Supplementary information: Supplementary data are available at Bioinformatics online.

Journal Article.  1124 words.  Illustrated.

Subjects: Bioinformatics and Computational Biology

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