Journal Article

CRISPI: a CRISPR interactive database

Christine Rousseau, Mathieu Gonnet, Marc Le Romancer and Jacques Nicolas

in Bioinformatics

Volume 25, issue 24, pages 3317-3318
Published in print December 2009 | ISSN: 1367-4803
Published online October 2009 | e-ISSN: 1460-2059 | DOI: http://dx.doi.org/10.1093/bioinformatics/btp586

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Summary: The CRISPR genomic structures (Clustered Regularly Interspaced Short Palindromic Repeats) form a family of repeats that is largely present in archaea and frequent in bacteria. On the basis of a formal model of CRISPR using very few parameters, a systematic study of all their occurrences in all available genomes of Archaea and Bacteria has been carried out. This has resulted in a relational database, CRISPI, which also includes a complete repertory of associated CRISPR-associated genes (CAS). A user-friendly web interface with many graphical tools and functions allows users to extract results, find CRISPR in personal sequences or calculate sequence similarity with spacers.

Availability: CRISPI free access at http://crispi.genouest.org

Contact: croussea@irisa.fr; jnicolas@irisa.fr;

Journal Article.  1362 words.  Illustrated.

Subjects: Bioinformatics and Computational Biology

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