Journal Article

ChiBE: interactive visualization and manipulation of BioPAX pathway models

Ozgun Babur, Ugur Dogrusoz, Emek Demir and Chris Sander

in Bioinformatics

Volume 26, issue 3, pages 429-431
Published in print February 2010 | ISSN: 1367-4803
Published online December 2009 | e-ISSN: 1460-2059 | DOI: http://dx.doi.org/10.1093/bioinformatics/btp665
ChiBE: interactive visualization and manipulation of BioPAX pathway models

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Summary: Representing models of cellular processes or pathways in a graphically rich form facilitates interpretation of biological observations and generation of new hypotheses. Solving biological problems using large pathway datasets requires software that can combine data mapping, querying and visualization as well as providing access to diverse data resources on the Internet. ChiBE is an open source software application that features user-friendly multi-view display, navigation and manipulation of pathway models in BioPAX format. Pathway views are rendered in a feature-rich format, and may be laid out and edited with state-of-the-art visualization methods, including compound or nested structures for visualizing cellular compartments and molecular complexes. Users can easily query and visualize pathways through an integrated Pathway Commons query tool and analyze molecular profiles in pathway context.

Availability: http://www.bilkent.edu.tr/%7Ebcbi/chibe.html

Contact: ugur@cs.bilkent.edu.tr

Supplementary information: Supplementary data are available at Bioinformatics online.

Journal Article.  1286 words.  Illustrated.

Subjects: Bioinformatics and Computational Biology

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