Journal Article

GWAF: an R package for genome-wide association analyses with family data

Ming-Huei Chen and Qiong Yang

in Bioinformatics

Volume 26, issue 4, pages 580-581
Published in print February 2010 | ISSN: 1367-4803
Published online December 2009 | e-ISSN: 1460-2059 | DOI: http://dx.doi.org/10.1093/bioinformatics/btp710
GWAF: an R package for genome-wide association analyses with family data

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Summary: GWAF, Genome-Wide Association analyses with Family, is an R package designed for GWAF. It implements association tests between a batch of genotyped or imputed single nucleotide polymorphisms (SNPs) and a binary or continuous trait with user specified genetic model, and generates informative results from the analyses. In addition, GWAF provides functions to visualize results. We evaluated GWAF using a simulated continuous trait and a binary trait dichotomized from the simulated continuous trait with real genotype data from the Framingham Heart Study's SNP Health Association Resource project.

Availability: http://cran.r-project.org/web/packages/GWAF/

Contact: qyang@bu.edu

Supplementary information: Supplementary data are available at Bioinformatics online.

Journal Article.  1531 words.  Illustrated.

Subjects: Bioinformatics and Computational Biology

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