Journal Article

BioNet: an R-Package for the functional analysis of biological networks

Daniela Beisser, Gunnar W. Klau, Thomas Dandekar, Tobias Müller and Marcus T. Dittrich

in Bioinformatics

Volume 26, issue 8, pages 1129-1130
Published in print April 2010 | ISSN: 1367-4803
Published online February 2010 | e-ISSN: 1460-2059 | DOI: https://dx.doi.org/10.1093/bioinformatics/btq089
BioNet: an R-Package for the functional analysis of biological networks

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Motivation: Increasing quantity and quality of data in transcriptomics and interactomics create the need for integrative approaches to network analysis. Here, we present a comprehensive R-package for the analysis of biological networks including an exact and a heuristic approach to identify functional modules.

Results: The BioNet package provides an extensive framework for integrated network analysis in R. This includes the statistics for the integration of transcriptomic and functional data with biological networks, the scoring of nodes as well as methods for network search and visualization.

Availability: The BioNet package and a tutorial are available from http://bionet.bioapps.biozentrum.uni-wuerzburg.de

Contact: marcus.dittrich@biozentrum.uni-wuerzburg.de; tobias.mueller@biozentrum.uni-wuerzburg.de

Journal Article.  901 words.  Illustrated.

Subjects: Bioinformatics and Computational Biology

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