Journal Article

TopoGSA: network topological gene set analysis

Enrico Glaab, Anaïs Baudot, Natalio Krasnogor and Alfonso Valencia

in Bioinformatics

Volume 26, issue 9, pages 1271-1272
Published in print May 2010 | ISSN: 1367-4803
Published online March 2010 | e-ISSN: 1460-2059 | DOI: https://dx.doi.org/10.1093/bioinformatics/btq131

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Summary: TopoGSA (Topology-based Gene Set Analysis) is a web-application dedicated to the computation and visualization of network topological properties for gene and protein sets in molecular interaction networks. Different topological characteristics, such as the centrality of nodes in the network or their tendency to form clusters, can be computed and compared with those of known cellular pathways and processes.

Availability: Freely available at http://www.infobiotics.net/topogsa

Contact: nxk@cs.nott.ac.uk; avalencia@cnio.es

Journal Article.  1521 words.  Illustrated.

Subjects: Bioinformatics and Computational Biology

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