Journal Article

Utilization of magnetoencephalography results to obtain favourable outcomes in epilepsy surgery

Michael J. M. Fischer, Gabriela Scheler and Hermann Stefan

in Brain

Published on behalf of The Guarantors of Brain

Volume 128, issue 1, pages 153-157
Published in print January 2005 | ISSN: 0006-8950
Published online November 2004 | e-ISSN: 1460-2156 | DOI: http://dx.doi.org/10.1093/brain/awh333
Utilization of magnetoencephalography results to obtain favourable outcomes in epilepsy surgery

Show Summary Details

Preview

Magnetoencephalography (MEG) is a well-known technique in the presurgical evaluation of epilepsy patients. Like EEG, it can detect and localize epileptic activity. Epilepsy surgery can be used to evaluate MEG source localizations. Resection volumes were determined in 33 epilepsy surgery patients. The resection volume, taken together with the post-operative outcome, was used to evaluate MEG results. The scattering MEG localizations of interictal epileptic activity were represented by an ellipsoidal volume. Using this MEG results ellipsoid, it was demonstrated that a high coverage by the resection volume and a small distance to the resection volume are both correlated to a favourable outcome; in addition, a homogeneous distribution of MEG localizations is correlated to a favourable outcome. This study shows that MEG source localization can help to delineate epileptic activity and, along with other techniques, should be taken into account for epilepsy surgery.

Keywords: MEG; presurgical evaluation; functional tailoring; MSI epilepsy surgery; epilepsy; MEG = magnetoencephalography; MSI = magnetic source imaging

Journal Article.  3267 words.  Illustrated.

Subjects: Neurology ; Neuroscience

Full text: subscription required

How to subscribe Recommend to my Librarian

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.