Journal Article

p53 from pathway to therapy

David Lane

in Carcinogenesis

Volume 25, issue 7, pages 1077-1081
Published in print July 2004 | ISSN: 0143-3334
Published online July 2004 | e-ISSN: 1460-2180 | DOI:
p53 from pathway to therapy

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  • Clinical Cytogenetics and Molecular Genetics


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In the 25 years since its first description the p53 protein has been shown to play a key role in both tumour suppression and aging. New discoveries about the function and control of p53 continue to emerge every month and attempts to exploit the system to develop better therapeutics and diagnostics are beginning to be successful in the clinic (1,2).

Journal Article.  4292 words.  Illustrated.

Subjects: Clinical Cytogenetics and Molecular Genetics

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