Journal Article

2009 Pandemic Influenza A (H1N1) Deaths among Children—United States, 2009–2010

Chad M. Cox, Lenee Blanton, Rosaline Dhara, Lynnette Brammer and Lyn Finelli

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 52, issue suppl_1, pages S69-S74
Published in print January 2011 | ISSN: 1058-4838
Published online January 2011 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1093/cid/ciq011
2009 Pandemic Influenza A (H1N1) Deaths among Children—United States, 2009–2010

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The 2009 pandemic influenza A (H1N1) (pH1N1) virus emerged in the United States in April 2009 (1) and has since caused significant morbidity and mortality worldwide (2–6). We compared pandemic influenza A (H1N1) (pH1N1)–associated deaths occurring from 15 April 2009 through 23 January 2010 with seasonal influenza–associated deaths occurring from 1 October 2007 through 14 April 2009, a period during which data collected were most comparable. Among 317 children who died of pH1N1-associated illness, 301 (95%) had a reported medical history. Of those 301, 205 (68%) had a medical condition associated with an increased risk of severe illness from influenza. Children who died of pH1N1-associated illness had a higher median age (9.4 vs 6.2 years; P<.01) and longer time from onset of symptoms to death (7 vs 5 days, P<.01) compared with children who died of seasonal influenza–associated illness. The majority of pediatric deaths from pH1N1 were in older children with high-risk medical conditions. Vaccination continues to be critical for all children, especially those at increased risk of influenza-related complications.

Journal Article.  3500 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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