Journal Article

Not Community-Associated Methicillin-Resistant <i>Staphylococcus aureus</i> (CA-MRSA)! A Clinician's Guide to Community MRSA - Its Evolving Antimicrobial Resistance and Implications for Therapy

Kyra Chua, Frederic Laurent, Geoffrey Coombs, M. Lindsay Grayson and Benjamin P. Howden

Edited by George M. Eliopoulous

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 52, issue 1, pages 99-114
Published in print January 2011 | ISSN: 1058-4838
Published online January 2011 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1093/cid/ciq067
Not Community-Associated Methicillin-Resistant Staphylococcus aureus (CA-MRSA)! A Clinician's Guide to Community MRSA - Its Evolving Antimicrobial Resistance and Implications for Therapy

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There is significant diversity in methicillin-resistant Staphylococcus aureus (MRSA) clones arising in the community worldwide, with considerable geographical differences in typical antimicrobial resistance profiles. Many community clones of MRSA have a non–multidrug resistant antimicrobial profile, providing increased options for empirical and directed therapy of infections caused by these strains. However, the recent description of increasing non–β lactam resistance in community clones of MRSA, especially USA300, provides a timely warning for clinicians making decisions about therapy for patients potentially infected with these strains. Continued monitoring of global epidemiology and emerging drug resistance data is critical for the effective management of these infections.

Journal Article.  6213 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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