Journal Article

Identification and Selection of Cases and Controls in the Pneumonia Etiology Research for Child Health Project

Maria Deloria-Knoll, Daniel R. Feikin, J. Anthony G. Scott, Katherine L. O’Brien, Andrea N. DeLuca, Amanda J. Driscoll and Orin S. Levine

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 54, issue suppl_2, pages S117-S123
Published in print April 2012 | ISSN: 1058-4838
Published online April 2012 | e-ISSN: 1537-6591 | DOI: https://dx.doi.org/10.1093/cid/cir1066
Identification and Selection of Cases and Controls in the Pneumonia Etiology Research for Child Health Project

More Like This

Show all results sharing these subjects:

  • Infectious Diseases
  • Immunology
  • Public Health and Epidemiology
  • Microbiology

GO

Show Summary Details

Preview

Methods for the identification and selection of patients (cases) with severe or very severe pneumonia and controls for the Pneumonia Etiology Research for Child Health (PERCH) project were needed. Issues considered include eligibility criteria and sampling strategies, whether to enroll hospital or community controls, whether to exclude controls with upper respiratory tract infection (URTI) or nonsevere pneumonia, and matching criteria, among others. PERCH ultimately decided to enroll community controls and an additional human immunodeficiency virus (HIV)–infected control group at high HIV-prevalence sites matched on age and enrollment date of cases; controls with symptoms of URTI or nonsevere pneumonia will not be excluded. Systematic sampling of cases (when necessary) and random sampling of controls will be implemented. For each issue, we present the options that were considered, the advantages and disadvantages of each, the rationale for the methods selected for PERCH, and remaining implications and limitations.

Journal Article.  4243 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

Full text: subscription required

How to subscribe Recommend to my Librarian

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.