Journal Article

Specimen Collection for the Diagnosis of Pediatric Pneumonia

Laura L. Hammitt, David R. Murdoch, J. Anthony G. Scott, Amanda Driscoll, Ruth A. Karron, Orin S. Levine and Katherine L. O’Brien

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 54, issue suppl_2, pages S132-S139
Published in print April 2012 | ISSN: 1058-4838
Published online April 2012 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1093/cid/cir1068
Specimen Collection for the Diagnosis of Pediatric Pneumonia

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Diagnosing the etiologic agent of pneumonia has an essential role in ensuring the most appropriate and effective therapy for individual patients and is critical to guiding the development of treatment and prevention strategies. However, establishing the etiology of pneumonia remains challenging because of the relative inaccessibility of the infected tissue and the difficulty in obtaining samples without contamination by upper respiratory tract secretions. Here, we review the published and unpublished literature on various specimens available for the diagnosis of pediatric pneumonia. We discuss the advantages and limitations of each specimen, and discuss the rationale for the specimens to be collected for the Pneumonia Etiology Research for Child Health study.

Journal Article.  4749 words. 

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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