Journal Article

Cloning, Sequencing and Mapping of a Manganese Superoxide Dismutase Gene of the Nematode <i>Caenorhabditis elegans</i>

Norio Suzuki, Kaoru Inokuma, Kayo Yasuda and Naoaki Ishii

in DNA Research

Published on behalf of Kazusa DNA Research Institute

Volume 3, issue 3, pages 171-174
Published in print January 1996 | ISSN: 1340-2838
Published online January 1996 | e-ISSN: 1756-1663 | DOI: http://dx.doi.org/10.1093/dnares/3.3.171

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We have cloned, sequenced and mapped a gene (sod-2) encoding manganese superoxide dismutase [EC 1.15.1.1] from the nematode Caenorhabditis elegans. The sod-2 was mapped to chromosome I by hybridization with a YAC polytene filter. The protein-coding region spans 1129 base pairs including 4 introns and encodes a protein of 221 amino acids (aa) (Mr = 24536) of which the first 24 aa are the presumed mitochondorial-targeting signal peptide. The gene sequence of sod-2 was slightly different from an isoform, sod-3.

Keywords: Manganese superoxide dismutase; sod-2; C. elegans; cDNA sequence; genomic sequence

Journal Article.  0 words. 

Subjects: Genetics and Genomics

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