Journal Article

Complementary DNA Cloning and Chromosomal Mapping of a Novel Phosphatidylinositol Kinase Gene

Toshiyuki Saito, Naohiko Seki, Hideshi Ishii, Miki Ohira, Akiko Hayashi, Sumie Kozuma and Tada-aki Hori

in DNA Research

Published on behalf of Kazusa DNA Research Institute

Volume 4, issue 4, pages 301-305
Published in print January 1997 | ISSN: 1340-2838
Published online January 1997 | e-ISSN: 1756-1663 | DOI: http://dx.doi.org/10.1093/dnares/4.4.301

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A cDNA for a putative new member for phosphatidylinositol kinase family was cloned from an adult human whole brain cDNA library. The predicted translation product was composed of 961 amino acid residues and contained a sequence feature characteristic for lipid/protein kinases. The messenger RNA was ubiquitously expressed in various tissues, while relatively higher expression was observed in heart, skeletal muscle and testis. The chromosomal location of the gene was determined by fluorescence in situ hybridization and PCR-based analyses with both a human/rodent monochromosomal hybrid cell panel and a radiation hybrid mapping panel.

Keywords: PI4 kinase; RT-PCR; 1q21

Journal Article.  0 words. 

Subjects: Genetics and Genomics

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