Journal Article

Identification and Characterization of a Novel Trans-membrane Protein Gene, <i>pdh1</i>, from <i>Schizosaccharomyces pombe</i>

Hidekatsu Iha, Mitsuhiro Takimoto, Inaho Danjoh and Asao Fujiyama

in DNA Research

Published on behalf of Kazusa DNA Research Institute

Volume 4, issue 6, pages 393-396
Published in print January 1997 | ISSN: 1340-2838
Published online January 1997 | e-ISSN: 1756-1663 | DOI: http://dx.doi.org/10.1093/dnares/4.6.393

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We have cloned a new gene, pdh1, from genomic DNA of fission yeast Schizosaccharomyces pombe. pdh1 is actively transcribed as 1400-nucleotide mRNA in vegetatively growing cells and can code for a 226 amino acid polypeptide (pdh1p). Computational structural prediction has revealed that the pdh1p is a highly hydrophobic protein with seven transmembrane domains. The prediction has also detected a possible C-kinase phosphorylation site within the longest hydrophilic loop.

Keywords: fission yeast; membrane protein; transmembrane domain

Journal Article.  0 words. 

Subjects: Genetics and Genomics

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