Journal Article

cDNA Cloning, Tissue Distribution and Chromosomal Localization of the Human ID4 Gene

Muriel Rigolet, Tina Rich, Marie-Sylvie Gross-Morand, Denise Molina-Gomes, Evani Viegas-Pequignot and Claudine Junien

in DNA Research

Published on behalf of Kazusa DNA Research Institute

Volume 5, issue 5, pages 309-313
Published in print January 1998 | ISSN: 1340-2838
Published online January 1998 | e-ISSN: 1756-1663 | DOI: http://dx.doi.org/10.1093/dnares/5.5.309

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A cDNA encoding the human Id4 protein has been isolated from an astrocytoma library. The predicted protein product shares 98% identity with the mouse Id4 protein and is markedly different from that already reported. By FISH analysis, the human ID4 gene was more precisely mapped to chromosome 6p22.3-p23. Northern blot analysis showed that ID4 is mainly expressed in thyroid, brain and fetal tissue and in some nervous system tumor cell lines.

Keywords: ID gene; HLH protein; Brain tumors

Journal Article.  0 words. 

Subjects: Genetics and Genomics

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