Journal Article

Genomic Structure and Localization of the Human Protein Phosphatase 2A BRγ Regulatory Subunit

Rosarelis Torres, Susan E. Ide, Anindya Dehejia, Alexander Baras and Mihael H. Polymeropoulos

in DNA Research

Published on behalf of Kazusa DNA Research Institute

Volume 6, issue 5, pages 323-327
Published in print January 1999 | ISSN: 1340-2838
Published online January 1999 | e-ISSN: 1756-1663 | DOI:

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In the course of our analysis of genomic sequence from the human chromosome 4p16.1 region harboring both the Wolfram and Ellis van Creveld syndrome genes1,2 we have identified a sequence with high homology (98% at the amino acid level) to the rat cDNA coding for the protein phosphatase 2A BRγ (PP2ABRγ) regulatory subunit. Although the human cDNAs for both the BRα and BRβ isoforms have been described previously, the BRγ subunit has not yet been identified in humans. Here we describe the precise genomic organization and genetic localization of the human PP2ABRγ. gene.

Keywords: Human PP2ABR; genomic sequence annotation; BAC contig; intron-exon structure

Journal Article.  0 words. 

Subjects: Genetics and Genomics

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