Journal Article

Cytotoxicity and shear bond strength of four orthodontic adhesive systems

Erwin Jonke, Alexander Franz, Josef Freudenthaler, Franz König, Hans-Peter Bantleon and Andreas Schedle

in The European Journal of Orthodontics

Published on behalf of European Orthodontics Society

Volume 30, issue 5, pages 495-502
Published in print October 2008 | ISSN: 0141-5387
Published online September 2008 | e-ISSN: 1460-2210 | DOI:
Cytotoxicity and shear bond strength of four orthodontic adhesive systems

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The objective of this study was to compare the cytotoxicity of four orthodontic bonding systems, Light Bond™, Enlight™, Concise™, and Transbond™, and to evaluate their shear bond strength (SBS). These orthodontic bonding materials were applied to metal brackets (Mini Diamond™). Glass specimens were used as controls in all experiments. Only Concise™ was a chemically cured system, the other systems were light cured. The specimens were added to L-929 fibroblast cultures immediately after fabrication or after pre-incubation for 7 days. The incubation time was 72 hours and the cells were counted by flow cytometry. One hundred and fifty-seven freshly extracted human third molars were used for testing the SBS in a universal testing machine. Statistical significance was determined using analysis of variance followed by post hoc comparisons for multiple-level alpha control.

Pairwise comparisons showed a significant difference only between Light Bond™ and Concise™ (P = 0.0126). The highest SBS was obtained with Light Bond™ (23.23 ± 1.53 MPa) followed by Transbond™ (20.39 ± 1.18 MPa) and Enlight™, (20.32 ± 1.06 MPa). Concise™ (17.87 ± 1.04 MPa) showed the lowest SBS. The cytotoxicity of all light-cured systems for fresh specimens was comparable, whereas the chemically cured system, Concise™, was significantly more cytotoxic. After 7 days of pre-incubation, all systems were significantly less cyotoxic than fresh specimens (P < 0.001). Brackets alone were not cytotoxic. All bonding systems showed a clinically satisfactory bond strength higher than 10 MPa, with the chemically cured system showing the lowest SBS.

Journal Article.  4626 words.  Illustrated.

Subjects: Restorative Dentistry and Orthodontics

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