Journal Article

Management and Conduct of Randomized Controlled Trials

Genell L. Knatterud

in Epidemiologic Reviews

Published on behalf of Johns Hopkins Bloomberg School of Public Health

Volume 24, issue 1, pages 12-25
Published in print July 2002 | ISSN: 0193-936X
Published online July 2002 | e-ISSN: 1478-6729 | DOI: http://dx.doi.org/10.1093/epirev/24.1.12
Management and Conduct of Randomized Controlled Trials

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In preparing to undertake a clinical trial, it may be helpful to keep in mind Fredrickson's description of clinical trials (31): “Field trials are indispensable. They will continue to be an ordeal. They lack glamour, they strain our resources and patience, and they protract the moment of truth to excruciating limits. Still, they are among the most challenging tests of our skills. I have no doubt that when the problem is well chosen, the study is appropriately designed, and that when all the populations concerned are made aware of the route and the goal, the reward can be commensurate with the effort. If, in major medical dilemmas, the alternative is to pay the costs of perpetual uncertainty, have we really any choice?”

Journal Article.  0 words. 

Subjects: Public Health and Epidemiology

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