Journal Article

Diabetes, left ventricular systolic dysfunction, and chronic heart failure

Michael R. MacDonald, Mark C. Petrie, Nathaniel M. Hawkins, John R. Petrie, Miles Fisher, Robert McKelvie, David Aguilar, Henry Krum and John J.V. McMurray

in European Heart Journal

Published on behalf of European Society of Cardiology

Volume 29, issue 10, pages 1224-1240
Published in print May 2008 | ISSN: 0195-668x
Published online April 2008 | e-ISSN: 1522-9645 | DOI: http://dx.doi.org/10.1093/eurheartj/ehn156
Diabetes, left ventricular systolic dysfunction, and chronic heart failure

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Chronic heart failure (HF) and diabetes mellitus (DM) commonly coexist. Each condition increases the likelihood of developing the other, and when they occur together in the same patient the risk of morbidity and mortality increases markedly. We discuss the epidemiological overlap and consider the complex patho-physiological pathways linking the two diseases. The treatment of each condition is made more problematic by the presence of the other. We review the evidence-based treatment strategies and discuss the common problems faced by physicians when treating patients with both conditions. This article forms a comprehensive overview of a fascinating intersection between two common diseases.

Keywords: Diabetes; Heart failure

Journal Article.  8915 words.  Illustrated.

Subjects: Cardiovascular Medicine

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