Journal Article

A 2-Year Follow-Up After a 2-Year RCT with Vitamin D and Exercise: Effects on Falls, Injurious Falls and Physical Functioning Among Older Women

Kirsti Uusi-Rasi, Radhika Patil, Saija Karinkanta, Pekka Kannus, Kari Tokola, Christel Lamberg-Allardt and Harri Sievänen

in Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences

Volume 72, issue 9, pages 1239-1245
Published in print September 2017 | ISSN: 1079-5006
Published online March 2017 | e-ISSN: 1758-535X | DOI: http://dx.doi.org/10.1093/gerona/glx044
A 2-Year Follow-Up After a 2-Year RCT with Vitamin D and Exercise: Effects on Falls, Injurious Falls and Physical Functioning Among Older Women

More Like This

Show all results sharing these subjects:

  • Geriatric Medicine
  • Public Health
  • Biological Sciences
  • Molecular and Cell Biology
  • Neuroscience

GO

Show Summary Details

Preview

Abstract

Background

Both exercise and vitamin D are recommended means to prevent falls among older adults, but their combined effects on fall-induced injuries are scarcely studied.

Methods

A 2-year follow-up of a previous 2-year randomized controlled trial with vitamin D and exercise (Ex) of 409 older home-dwelling women using a factorial 2 × 2 design (DEx, D+Ex, DEx+, D+Ex+). Besides monthly fall diaries, femoral neck bone mineral density (fn-BMD), and physical functioning were assessed at 1 and 2 years after the intervention.

Results

After the intervention, S-25OHD concentrations declined to baseline levels in both supplement groups. The groups did not differ for change in fn-BMD or physical functioning, except for leg extensor muscle strength, which remained about 10% greater in the exercise groups compared with the reference group (DEx). There were no between-group differences in the rate of all falls, but medically attended injurious falls reduced in D+Ex and DEx+ groups compared with DEx. However, all former treatment groups had less medically attended injured fallers, HRs (95% CI) being 0.62 (0.39–1.00) for D+Ex, 0.46 (0.28–0.76) for DEx+, and 0.55 (0.34–0.88) for D+Ex+, compared with DEx.

Conclusions

Exercise-induced benefits in physical functioning partly remained 2 years after cessation of supervised training. Although there was no difference in the rate of all falls, former exercise groups continued to have lower rate of medically attended injured fallers compared with referents even 2 years after the intervention. Vitamin D without exercise was associated with less injurious falls with no difference in physical functioning.

Keywords: Physical functioning; Injurious falls; Vitamin D; Exercise

Journal Article.  4912 words.  Illustrated.

Subjects: Geriatric Medicine ; Public Health ; Biological Sciences ; Molecular and Cell Biology ; Neuroscience

Full text: subscription required

How to subscribe Recommend to my Librarian

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.