Journal Article

Gene finding in genetically isolated populations

Peter Heutink and Ben A. Oostra

in Human Molecular Genetics

Volume 11, issue 20, pages 2507-2515
Published in print October 2002 | ISSN: 0964-6906
Published online October 2002 | e-ISSN: 1460-2083 | DOI: http://dx.doi.org/10.1093/hmg/11.20.2507
Gene finding in genetically isolated populations

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The struggle to identify susceptibility genes for complex disorders has stimulated geneticists to develop new approaches. One approach that has gained considerable interest is to focus on genetically isolated populations rather than on the general population. There remains much controversy and theoretical debate over the feasibility and advantages of such populations, but recent results speak in favor of the feasibility of this approach, and will be reviewed here.

Journal Article.  7043 words.  Illustrated.

Subjects: Genetics and Genomics

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