Journal Article

Errata

in Human Molecular Genetics

Volume 8, issue 13, pages 2573-2573
Published in print December 1999 | ISSN: 0964-6906
Published online December 1999 | e-ISSN: 1460-2083 | DOI: http://dx.doi.org/10.1093/hmg/8.13.2573a
Errata

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Cis and trans Effects of the Myotonic Dystrophy (DM) Mutation in a Cell Culture Model

Jeffrey D. Amack, Aileen P. Paguio and Mani S. Mahadevan

Human Molecular Genetics 8, 1975–1984 (1999)

The legend to Figure 2 was erroneously cropped in the printed version. It is reproduced below in its entirety: Figure 2. Nuclear RNA foci formation. RNA-FISH analysis with a CY3 fluorescently labeled (CAG)10 oligonucleotide probe (red) detected RNA foci in the nuclei of fibroblasts from a DM patient (B) but not an unaffected individual (A). RNA foci were also detected in C2C12 myoblasts transiently transfected with CAT reporter constructs containing a mutant DMPK 3′-UTR (57, 78 or 200 CTG repeats) (E)ora(CTG)100 expansion only (F). Foci were not detected in cells transfected with a construct containing a normal DMPK 3′-UTR (D) or a control CAT vector (C) Indirect immunostaining with anti-CAT antibody identified transfected cells (green) and nuclei were counterstained with DAPI (blue).

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Subjects: Genetics and Genomics

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