Journal Article

Epigenetic regulation of stem cell fate

Victoria V. Lunyak and Michael G. Rosenfeld

in Human Molecular Genetics

Volume 17, issue R1, pages R28-R36
Published in print April 2008 | ISSN: 0964-6906
Published online April 2008 | e-ISSN: 1460-2083 | DOI: http://dx.doi.org/10.1093/hmg/ddn149
Epigenetic regulation of stem cell fate

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Stem cell-based regenerative medicine holds great promise for repair of diseased tissue. Modern directions in the field of epigenetic research aimed to decipher the epigenetic signals that give stem cells their unique ability to self-renew and differentiate into different cell types. However, this research is only the tip of the iceberg when it comes to writing an ‘epigenetic instruction manual’ for the ramification of molecular details of cell commitment and differentiation. In this review, we discuss the impact of the epigenetic research on our understanding of stem cell biology.

Journal Article.  5910 words.  Illustrated.

Subjects: Genetics and Genomics

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