Journal Article

B-003LUNG TRANSPLANTATION WITH DONORS 60 YEARS AND OLDER

I. Lopez, Alberto Jauregui, J. Sole, M. Deu, L. Romero, J. Perez, I. Bello, M. Wong and M. Canela

in Interactive CardioVascular and Thoracic Surgery

Published on behalf of European Association for Cardio-Thoracic Surgery

Volume 18, issue suppl_1, pages S1-S2
Published in print June 2014 | ISSN: 1569-9293
Published online June 2014 | e-ISSN: 1569-9285 | DOI: http://dx.doi.org/10.1093/icvts/ivu167.3
B-003LUNG TRANSPLANTATION WITH DONORS 60 YEARS AND OLDER

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  • Cardiovascular Medicine
  • Cardiothoracic Surgery

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Objectives: The objective of this study was to compare the outcomes in lung transplantation between organs from donors older and younger than 60 years.

Methods: We performed a retrospective observational study comparing the group of patients receiving organs from donors 60 years or older (group A) or younger than 60 years (group B). We analysed 293 consecutive adult lung transplants between January 2007 and December 2012, 75 (25.6%) in group A and 218 (74.4%) group B. Postoperative outcomes and global survival rate were evaluated. Pearson's chi-squared test, ANOVA, Mann-Whitney U test and Kaplan-Meier with log-rank test were used for comparisons.

Results: The percentage of donors 60 years and older used in our centre has been increasing from 12.2% in 2007 to 34.9% in 2012. The donor mean age was 63.7 years (range 60-71) in group A and 41.6 years (range 13-59) in group B. Regarding donor characteristics, there were fewer smokers (27% vs 42.9%; P = 0.016) and fewer donors with thoracic trauma (0% vs 5.6%; P = 0.038) or purulent secretions (4% vs 15.1%; P = 0.011) in group A. Regarding recipient characteristics, the mean age was higher in group A (54.7 vs 49.3 years; P < 0.001). The 30-day and in-hospital postoperative mortality in group A and B was 5.3% vs 9.2% (P = 0.291) and 14.7% vs 12% (P = 0.547). Postoperative morbidity and median hospital stay (32.5 vs 40 days; P = 0.160) were similar in both groups. There were no statistically significant differences between groups A and B in terms of survival at 1, 2 and 3 years: 79.7, 67.8 and 65.8% vs 81.1, 76.4 and 69.5% (P = 0.336).

Conclusions: Our results support the idea that donors older than 60 years can be used safely for lung transplantation with comparable results to younger donors in terms of postoperative outcomes and mid-term survival.

Disclosure: No significant relationships.

Journal Article.  0 words. 

Subjects: Cardiovascular Medicine ; Cardiothoracic Surgery

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