Journal Article

A novel method for collecting and detecting amoxycillin in urine: a tool for testing antibiotic compliance in the community

Wei Shen Lim, Sarah Gander, Roger G. Finch and John T. Macfarlane

in Journal of Antimicrobial Chemotherapy

Published on behalf of British Society for Antimicrobial Chemotherapy

Volume 46, issue 5, pages 835-837
Published in print November 2000 | ISSN: 0305-7453
Published online November 2000 | e-ISSN: 1460-2091 | DOI: https://dx.doi.org/10.1093/jac/46.5.835
A novel method for collecting and detecting amoxycillin in urine: a tool for testing antibiotic compliance in the community

More Like This

Show all results sharing these subjects:

  • Medical Oncology
  • Critical Care

GO

Show Summary Details

Preview

Assessing compliance to prescribed antibiotics in community studies of respiratory tract infections is difficult. We describe a simple method for collecting and detecting amoxycillin in urine using urine dip-sticks in conjunction with a bioassay. Urine was collected at timed intervals from eight healthy volunteers following oral amoxycillin administration. Dip-sticks inoculated with urine collected 1 and 8 h after antibiotic resulted in mean zones of inhibition of 1.75 and 1.37 cm, respectively. Amoxycillin activity remained demonstrable 14 days after inoculation of dip-sticks with urine. Dip-sticks inoculated with urine from control subjects who had not taken amoxycillin did not cause inhibition.

Journal Article.  1396 words. 

Subjects: Medical Oncology ; Critical Care

Full text: subscription required

How to subscribe Recommend to my Librarian

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.