Journal Article

Ciprofloxacin-resistant <i>Escherichia coli</i> from bacteraemias in England; increasingly prevalent and mostly from men

David M. Livermore, Tom Nichols, Theresa L. Lamagni, Nicola Potz, Rosy Reynolds and Georgia Duckworth

in Journal of Antimicrobial Chemotherapy

Published on behalf of British Society for Antimicrobial Chemotherapy

Volume 52, issue 6, pages 1040-1042
Published in print December 2003 | ISSN: 0305-7453
Published online December 2003 | e-ISSN: 1460-2091 | DOI: http://dx.doi.org/10.1093/jac/dkg479
Ciprofloxacin-resistant Escherichia coli from bacteraemias in England; increasingly prevalent and mostly from men

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Objectives: To assess ciprofloxacin resistance among Escherichia coli isolates from bacteraemia patients in England in relation to age, sex and Region.

Methods: Routine susceptibility data for bacteraemia isolates were collected from over 90% of hospitals in England.

Results: During 1995–2001, the prevalence of ciprofloxacin resistance trebled, from 2.1% to 6.5%. Isolates from men were more frequently resistant than those from women, possibly because infections in men more often involve nosocomial strains. Resistance was rare (<1.5%) in isolates from patients aged <1 year; among older patients, resistance was unrelated to age in isolates from women, but peaked in the 15–44 age group for men.

Conclusions: The prevalence of ciprofloxacin resistance in E. coli from bacteraemia is strongly associated with sex and, to a lesser extent, age.

Keywords: Keywords: E. coli, bacteraemia, gender, ciprofloxacin resistance

Journal Article.  1632 words. 

Subjects: Medical Oncology ; Critical Care

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