Journal Article

All for CD91 and CD91 for all

Justin Stebbing, Philip Savage, Steve Patterson and Brian Gazzard

in Journal of Antimicrobial Chemotherapy

Published on behalf of British Society for Antimicrobial Chemotherapy

Volume 53, issue 1, pages 1-3
Published in print January 2004 | ISSN: 0305-7453
Published online January 2004 | e-ISSN: 1460-2091 | DOI:
All for CD91 and CD91 for all

Show Summary Details


Heat shock proteins interact with antigen-presenting cells through their receptor, CD91, eliciting a cascade of events including maturation, activation and representation of chaperoned foreign peptides with class I molecules on their surface. In turn, this facilitates recognition of non-self leading to induction of a cytotoxic T cell response. The abundance of heat shock proteins in tumours and their presence in virion coats makes them attractive propositions for use in antitumour and antiviral strategies.

Keywords: Keywords: heat shock proteins, HIV, cancer, receptors

Journal Article.  2235 words. 

Subjects: Medical Oncology ; Critical Care

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