Journal Article

Characterization of major clones of antibiotic-resistant <i>Streptococcus pneumoniae</i> in New Zealand by multilocus sequence typing

David C. Bean and John D. Klena

in Journal of Antimicrobial Chemotherapy

Published on behalf of British Society for Antimicrobial Chemotherapy

Volume 55, issue 3, pages 375-378
Published in print March 2005 | ISSN: 0305-7453
Published online March 2005 | e-ISSN: 1460-2091 | DOI: http://dx.doi.org/10.1093/jac/dki001
Characterization of major clones of antibiotic-resistant Streptococcus pneumoniae in New Zealand by multilocus sequence typing

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  • Medical Oncology
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Objectives: To determine the relationship between New Zealand isolates of antibiotic-resistant Streptococcus pneumoniae and internationally widespread resistant clones.

Methods: Fifty-nine isolates representing both invasive and non-invasive pneumococci from multiple locations, serotypes and years were analysed by multilocus sequence typing.

Results: Major international clones, including Spain23F-1, France9V-3 and Taiwan19F-14, were found to be present in New Zealand. A one-allele variant of the Taiwan19F-14 clone (aroE 15→4, ST 271) was particularly prominent.

Conclusions: Antibiotic-resistant pneumococci have not evolved de novo in New Zealand, but were introduced to the country during the early 1990s.

Keywords: S. pneumoniae; PMEN; MLST

Journal Article.  1870 words.  Illustrated.

Subjects: Medical Oncology ; Critical Care

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