Journal Article

Improved compliance with a gentamicin prescribing policy after introduction of a monitoring form

Matthew S. Rogers, Mairi M. Cullen, Emma M. Boxall and Paul R. Chadwick

in Journal of Antimicrobial Chemotherapy

Published on behalf of British Society for Antimicrobial Chemotherapy

Volume 56, issue 3, pages 566-568
Published in print September 2005 | ISSN: 0305-7453
Published online August 2005 | e-ISSN: 1460-2091 | DOI:
Improved compliance with a gentamicin prescribing policy after introduction of a monitoring form

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Objectives: Compliance with our local hospital policy for gentamicin administration and monitoring was found to be inadequate on audit. A gentamicin monitoring form was introduced with the aim of improving staff compliance with the policy thus minimizing the risks of toxicity while ensuring adequate dosing.

Patients and methods: The initial audit examined the prescribing, administration and monitoring of intravenous gentamicin given to 20 patients. The introduction of a gentamicin monitoring form was prompted by unsatisfactory initial dosing and subsequent monitoring and adjustment of gentamicin doses.

Results: Following introduction of the monitoring form, the proportion of appropriate starting doses had increased from 13 out of 20 to 18 out of 20 prescriptions. The timing of initial serum levels was significantly better: 18 timed correctly, compared with 12 in initial audit. Subsequent administration and monitoring appeared more compliant with fewer doses inappropriately omitted and more levels checked appropriately. No improvement was seen in the quality of dose adjustment.

Conclusions: In conjunction with the support and advice of the pharmacy and microbiology departments, the use of a gentamicin monitoring form can improve the quality of intravenous gentamicin use in the hospital setting.

Keywords: nephrotoxicity; pharmacists; algorithm

Journal Article.  1644 words. 

Subjects: Medical Oncology ; Critical Care

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