Journal Article

Guidelines for the laboratory diagnosis and susceptibility testing of methicillin-resistant <i>Staphylococcus aureus</i> (MRSA)

Derek F. J. Brown, David I. Edwards, Peter M. Hawkey, Donald Morrison, Geoffrey L. Ridgway, Kevin J. Towner and Michael W. D. Wren

in Journal of Antimicrobial Chemotherapy

Published on behalf of British Society for Antimicrobial Chemotherapy

Volume 56, issue 6, pages 1000-1018
Published in print December 2005 | ISSN: 0305-7453
Published online December 2005 | e-ISSN: 1460-2091 | DOI: http://dx.doi.org/10.1093/jac/dki372
Guidelines for the laboratory diagnosis and susceptibility testing of methicillin-resistant Staphylococcus aureus (MRSA)

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These evidence-based guidelines have been produced after a literature review of the laboratory diagnosis and susceptibility testing of methicillin-resistant Staphylococcus aureus (MRSA). We have considered the detection of MRSA in screening samples and the detection of reduced susceptibility to glycopeptides in S. aureus. Recommendations are given for the identification of S. aureus and for suitable methods of susceptibility testing and screening for MRSA and for S. aureus with reduced susceptibility to glycopeptides. These guidelines indicate what tests should be used but not when the tests are applicable, as aspects of this are dealt with in guidelines on control of MRSA. There are currently several developments in screening media and molecular methods. It is likely that some of our recommendations will require modification as the new methods become available.

Keywords: MRSA identification; MRSA susceptibility testing; MRSA screening; MRSA molecular methods; GISA; meticillin

Journal Article.  15796 words. 

Subjects: Medical Oncology ; Critical Care

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