Journal Article

Diagnosis and treatment of prosthetic aortic graft infections: confusion and inconsistency in the absence of evidence or consensus

S. F. FitzGerald, C. Kelly and H. Humphreys

in Journal of Antimicrobial Chemotherapy

Published on behalf of British Society for Antimicrobial Chemotherapy

Volume 56, issue 6, pages 996-999
Published in print December 2005 | ISSN: 0305-7453
Published online November 2005 | e-ISSN: 1460-2091 | DOI: http://dx.doi.org/10.1093/jac/dki382
Diagnosis and treatment of prosthetic aortic graft infections: confusion and inconsistency in the absence of evidence or consensus

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Prosthetic aortic graft infections represent a major diagnostic and therapeutic challenge. Although a combination of clinical assessment, imaging and microbiological investigations is usually helpful, there are no agreed criteria to confirm a diagnosis. Potential pathogens isolated from superficial specimens may be misleading but influence the choice of antimicrobial agents. Removal of the infected material is strongly recommended. However, this is not always possible in the very debilitated or clinically unstable patient. The choice of which antimicrobial agents to administer as empirical or definitive therapy and the duration of treatment are unclear. A multi-disciplinary group is required to offer guidance, based on what evidence there is, and to provide expert consensus (as is the case for infective endocarditis) to optimize the management of these difficult infections.

Keywords: vascular grafts; antibiotics; management

Journal Article.  2790 words. 

Subjects: Medical Oncology ; Critical Care

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