Journal Article

Normal Values for Pentachlorophenol in Urine Samples Collected from a General Population

Ronald G. Treble and Thomas S. Thompson

in Journal of Analytical Toxicology

Volume 20, issue 5, pages 313-317
Published in print September 1996 | ISSN: 0146-4760
e-ISSN: 1945-2403 | DOI: http://dx.doi.org/10.1093/jat/20.5.313
Normal Values for Pentachlorophenol in Urine Samples Collected from a General Population

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Aliquots of urine samples collected over a 24-h period from normal individuals were analyzed for pentachlorophenol (PCP). Urine samples were taken from subjects living in various regions (both rural and urban) throughout the province of Saskatchewan. Urinary PCP concentrations were determined with gas chromatography-mass spectrometry and stable isotope dilution. The normal PCP concentrations were found to range from 0.05 to 3.6 ng/mL. Because the aliquots analyzed were taken from 24-h sample collections, the normal range of PCP excreted on a daily basis was determined. A total of 69 samples taken from 26 males and 43 females who ranged in age from 6 to 87 years were analyzed. The average amount of excreted PCP was determined to be 4.3 nmol/day.

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Subjects: Medical Toxicology ; Toxicology (Non-medical)

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