Journal Article

Concentrations of Heroin, 06-Monoacetylmorphine, and Morphine in a Lethal Case Following an Oral Heroin Overdose

Pok P. Rop, Monique Fornaris, Thierry Salmon, Joelle Burle and Mireille Bresson

in Journal of Analytical Toxicology

Volume 21, issue 3, pages 232-235
Published in print May 1997 | ISSN: 0146-4760
Published online May 1997 | e-ISSN: 1945-2403 | DOI: http://dx.doi.org/10.1093/jat/21.3.232
Concentrations of Heroin, 06-Monoacetylmorphine, and Morphine in a Lethal Case Following an Oral Heroin Overdose

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A case of lethal overdose by heroin ingestion is presented. The concentrations of drugs were measured several hours after death. Heroin, 06-monoacetylmorphine, and morphine were identified and quantitated in blood, urine, and gastrointestinal contents by gas chromatography-mass spectrometry and high-performance liquid chromatography. Concentrations of heroin, 06-monoacetylmorphine, and morphine were 109, 168, and 1140 ng/mL, respectively, in blood and 17, 12, and 425 ng/g, respectively, in gastrointestinal content. In urine, however, only morphine was detected at 3650 ng/mL.

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Subjects: Medical Toxicology ; Toxicology (Non-medical)

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