Journal Article

Accuracy of Five On-Site Immunoassay Drugs-of-Abuse Testing Devices

E. Howard Taylor, Ernest H. Oertli, Jana W. Wolfgang and Eric Mueller

in Journal of Analytical Toxicology

Volume 23, issue 2, pages 119-124
Published in print March 1999 | ISSN: 0146-4760
Published online March 1999 | e-ISSN: 1945-2403 | DOI: http://dx.doi.org/10.1093/jat/23.2.119
Accuracy of Five On-Site Immunoassay Drugs-of-Abuse Testing Devices

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Many current “on-site” urine drug-testing products claim performance equivalent to laboratory testing. Five commercially available products (PharmScreen™, Roche TestCup®, Accusign™ DOA 2, Status DS™, and American Bio Medica-Rapid Drug Screen) were challenged with quality-control specimens of known drug metabolite concentrations, 25% above and 25% below the SAMHSA cutoffs, and with known positive and negative donor specimens previously analyzed by immunoassay and gas chromatography-mass spectrometry. The results indicate discrepancies between claims and performance for all products, particularly with amphetamines. The implications for employer-based drug testing are discussed.

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Subjects: Medical Toxicology ; Toxicology (Non-medical)

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