Journal Article

Comparison of HPLC and GC-MS Methods for Determination of Embutramide (A Component of Tanax<sup>®</sup> or T-61<sup>®</sup> in Biological Specimens

M. Giorgi, S. Bertini, G. Soldani and M. Giusiani

in Journal of Analytical Toxicology

Volume 25, issue 5, pages 323-327
Published in print July 2001 | ISSN: 0146-4760
Published online July 2001 | e-ISSN: 1945-2403 | DOI: http://dx.doi.org/10.1093/jat/25.5.323
Comparison of HPLC and GC-MS Methods for Determination of Embutramide (A Component of Tanax® or T-61® in Biological Specimens

More Like This

Show all results sharing these subjects:

  • Medical Toxicology
  • Toxicology (Non-medical)

GO

Show Summary Details

Preview

Tanax or T-61, a euthanasia solution commonly used in veterinary medicine, has been often involved in suicide attempts (humans) and malicious intoxications (animals). For forensic reasons, the identification of one or more of the three components (embutramide, mebenzonium iodide, and tetracaine hydrochloride) of Tanax is needed to confirm the hypothesis of intoxication. This study was performed with new high-performance liquid chromatographic and gas chromatographic-mass spectrometric methods to identify embutramide in biological matrices (blood, liver, kidney) from different animal species. The good sensitivity and specificity of both methods recommend their use in toxicological analysis in both human and veterinary medicine.

Journal Article.  0 words. 

Subjects: Medical Toxicology ; Toxicology (Non-medical)

Full text: subscription required

How to subscribe Recommend to my Librarian

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.