Journal Article

Tissue Distribution of Xylazine in a Suicide by Hanging

Karla A. Moore, Mary G. Ripple, Saffia Sakinedzad, Barry Levine and David R. Fowler

in Journal of Analytical Toxicology

Volume 27, issue 2, pages 110-112
Published in print March 2003 | ISSN: 0146-4760
Published online March 2003 | e-ISSN: 1945-2403 | DOI: http://dx.doi.org/10.1093/jat/27.2.110
Tissue Distribution of Xylazine in a Suicide by Hanging

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Xylazine (Rompun®, Sedazine®, AnaSed®) is currently the most commonly used sedative-analgesic in veterinary medicine. There are nine published cases of xylazine's involvement in human drug-related deaths and impairment. However, blood concentrations were reported in only four of these cases. Three of these nine cases were fatalities involving xylazine, two of which involved xylazine alone but did not report blood concentrations because of extensive decomposition of the bodies. This report documents a case in which xylazine alone was identified in a suicide by hanging. The following xylazine concentrations were found: 2.3 mg/L in heart blood; 2.9 mg/L in peripheral (subclavian) blood; 6.3 mg/L in bile; 0.01 mg/L in urine; 6.1 mg/kg in liver; and 7.8 mg/kg in kidney.

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Subjects: Medical Toxicology ; Toxicology (Non-medical)

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