Journal Article

Tizanidine Distribution in a Postmortem Case*

Jason H. Sklerov, Dawn E. Cox, Karla A. Moore, Barry Levine and David Fowler

in Journal of Analytical Toxicology

Volume 30, issue 5, pages 331-334
Published in print June 2006 | ISSN: 0146-4760
Published online June 2006 | e-ISSN: 1945-2403 | DOI: http://dx.doi.org/10.1093/jat/30.5.331
Tizanidine Distribution in a Postmortem Case*

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The case of a 57-year-old white female who was found deceased at home by her husband is presented. A suicide note was found at the scene. No remarkable findings were observed at autopsy. Comprehensive toxicological analysis of the heart blood identified ethanol (0.16 g/dL), diazepam (1.1 mg/L), and tizanidine (2.3 mg/L). Blood concentrations of tizanidine following therapeutic use do not exceed 0.025 mg/L. The medical examiner ruled that the cause of death was combined ethanol and multiple drug intoxication, and the manner of death was suicide.

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Subjects: Medical Toxicology ; Toxicology (Non-medical)

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