Journal Article

A MAP Kinase Cascade That Controls Plant Cytokinesis

Yuji Takahashi, Takashi Soyano, Michiko Sasabe and Yasunori Machida

in The Journal of Biochemistry

Published on behalf of The Japanese Biochemical Society

Volume 136, issue 2, pages 127-132
Published in print August 2004 | ISSN: 0021-924X
Published online August 2004 | e-ISSN: 1756-2651 | DOI:
A MAP Kinase Cascade That Controls Plant Cytokinesis

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Several components of mitogen-activated protein kinase (MAPK) cascades have been identified in higher plants and have been implicated in cellular responses to a wide variety of abiotic and biotic stimuli. Our recent work has demonstrated that a MAP kinase cascade is involved in the regulation of cytokinesis in plant cells. The MAP kinase cascade in tobacco includes NPK1 MAPK kinase kinase, NQK1 MAPK kinase, and NRK1 MAPK, and its activation is triggered by the binding of NACK1/2 kinesin-like protein to the NPK1 MAPK kinase kinase at the late M-phase of the cell cycle. We refer to this cascade as the NACK-PQR pathway. In this review, we introduce a mechanism for the regulation of plant cytokinesis, focusing on the role of the NACK-PQR pathway.

Keywords: plant cytokinesis, NACK1, NPK1 MAPKKK, NQK1 MAPKK, NRK1 MAPK.; BFA, brefeldin A; DAPI, 4′,6-diamidino-2-phenylindole; GFP, green fluorescent protein; KLP, kinesin-like protein; MAPs, MT-associated proteins; MAPK, mitogen-activated protein kinase; MAPKK, MAPK kinase; MAPKKK, MAPKK kinase; MT, microtubule; NACK1, NPK1-activating kinesin-like protein; NPK1, nucleus- and phragmoplast-localized protein kinase.

Journal Article.  4202 words.  Illustrated.

Subjects: Biochemistry

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