Journal Article

Live Show of Rho GTPases in Cell Migration

Xiumin Yan, Yidong Shen and Xueliang Zhu

in Journal of Molecular Cell Biology

Published on behalf of Chinese Academy of Sciences

Volume 2, issue 2, pages 68-69
Published in print April 2010 | ISSN: 1674-2788
Published online December 2009 | e-ISSN: 1759-4685 | DOI: https://dx.doi.org/10.1093/jmcb/mjp039
Live Show of Rho GTPases in Cell Migration

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Rho GTPases, including RhoA, Rac1 and Cdc42, are key regulators of cell migration in animals. In a recent issue of Nature, two papers present delicate studies on precise roles and spatiotemporal coordination of Rho GTPases in live cells, using either a photoactivatable Rac1 or specific biosensors, together with computational multiplexing method. In addition to implications in cell migration, analytical tools and methods used in these works can also be extended into other live cell studies on complex cellular/molecular events.

Journal Article.  1205 words.  Illustrated.

Subjects: Molecular and Cell Biology

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