Chapter

Parkinson's disease

Ivan Donaldson, C. David Marsden, Susanne A. Schneider and Kailash P. Bhatia

in Marsden's Book of Movement Disorders

Published on behalf of Oxford University Press

ISBN: 9780192619112
Published online January 2012 | e-ISBN: 9780199698103 | DOI: http://dx.doi.org/10.1093/med/9780192619112.003.0150
Parkinson's disease

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Idiopathic Parkinson’s disease is a clinical syndrome characterized by the gradual onset and progression of tremor, rigidity, akinesia, and defects of posture and locomotion and various non-motor symptoms, not due to any other recognized cause. Idiopathic Parkinson’s disease is defined as the clinical syndrome of parkinsonism associated with a distinctive pathology comprising degeneration of pigmented brainstem nuclei, including the dopaminergic substantia nigra pars compacta, with the presence of Lewy bodies in remaining nerve cells.

Chapter.  196080 words.  Illustrated.

Subjects: Neurology

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