Chapter

Management of Elevated Intracranial Pressure

Michael T. Froehler

in Principles of Drug Therapy in Neurology

Second edition

Published on behalf of Oxford University Press

Published in print September 2010 | ISBN: 9780195146837
Published online April 2013 | e-ISBN: 9780199322961 | DOI: http://dx.doi.org/10.1093/med/9780195146837.003.0350

Series: Contemporary Neurology Series

Management of Elevated Intracranial Pressure

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Raised intracranial pressure (ICP) can significantly contribute to brain injury. It most often occurs as a result of acute neurologic insults, but it also exists as a chronic idiopathic condition. In the intensive care unit, elevated ICP is frequently associated with neurologic diseases including trauma, stroke, and intracranial hemorrhage as well as with systemic diseases such as hypertensive emergencies, hepatic failure, and a host of metabolic derangements. If untreated, elevated ICP can lead to further neurologic injury and death, whereas attention to ICP allows for the timely management of these life-threatening emergencies. A thorough understanding of ICP pathophysiology can help the clinician to identify patients with elevated ICP, and can guide rapid and informed decision making in the critical care setting. With that goal in mind, this chapter will review the normal physiology of ICP, discuss the mechanisms by which ICP can become disordered, and review the available treatment options.

Chapter.  18765 words.  Illustrated.

Subjects: Neurology

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