Gavril W. Pasternak and Richard Payne

in Principles of Drug Therapy in Neurology

Second edition

Published on behalf of Oxford University Press

Published in print September 2010 | ISBN: 9780195146837
Published online April 2013 | e-ISBN: 9780199322961 | DOI:

Series: Contemporary Neurology Series


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The International Association for the Study of Pain classifies pain as an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage.1 However, the perception of pain for an individual remains very subjective and is related to nociceptive input in a very complex and poorly understood manner.2 Nonetheless, advances in our understanding of the neuropharmacology and neurophysiology of pain and nociception have provided a more rational basis for therapy of acute and chronic pain in people.3 This chapter will review current concepts of the mechanisms of pain and nociception and its pharmacological management.

Chapter.  12873 words.  Illustrated.

Subjects: Neurology ; Pain Medicine

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